Booking airfare can be a stressful experience.  You always want to be sure you've got the best deal, but surely, you're way too busy to sit around stalking websites to save a piddly $25. Unless you've got your own personal assistant, you've got to ask yourself what your time is worth before you spend hours at the computer.  When you do shop around, make sure you're working with the best discount websites and give them a quick run down before you buy.  You can almost bet you're getting the best deal and in fact, some websites guarantee it.

Savvy Scoop: We usually use the search engines to find the best deal and book directly with the airlines if the price is the same.  If you have to make changes to your flight, it'll be easier to deal directly with the airline.

BOOKING FLIGHTS (Best Search Engines, Hands Down)
kayak.com
vayama.com
mobissimo.com
orbitz.com

FARE PREDICTIONS
Bing.com/travel - Enter your destinations and this site will make recommendations on when to buy or wait, with a confidence rating, giving you all the tools you need to know when to make your move.

FLIGHT DISCOUNT ALERTS
Airfarewatchdog.com - If you've got a little time before you need to book, enter your destination and date parameters into this search engine and you can expect alerts on great deals right in your inbox.

BEST SEATS
Seatguru.com - If you're always getting that unfortunate non-reclining seat right near the toilet, check out this site to find out which are the best spots on the plane. 

BEST AIRPORT EXPERIENCE
Ifly.com - Whether you've got a long layover or need to see how fast you're going to have to run to make your connection, you can get all the dish you need to make the most of your airport time.